Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050666 | 0.87 | MLYCD (0.41) | RXRANR1H2NR1H3TSHRMLYCD | |
| SCHEMBL7667615 | 0.78 | LMNA (0.49) | RXRANR1H2NR1H3TSHRMLYCD | |
| SCHEMBL7670109 | 0.78 | PTPN1 (0.49) | PTPN1GSK3BMLYCDCES2CES1 | |
| SCHEMBL272401 | 0.77 | KIF11 (0.40) | RXRANR1H2NR1H3HTTMAPT | |
| SCHEMBL12252112 | 0.77 | PDK2 (0.41) | MLYCDSERPINE1 | |
| SCHEMBL5339338 | 0.75 | ATM (0.44) | GSK3BTSHRMAPTLMNA | |
| SCHEMBL5563726 | 0.74 | TSHR (0.54) | NR1H2NR1H3TSHRMLYCDHTT | |
| SCHEMBL2069707 | 0.74 | PDK2 (0.41) | RXRANR1H2NR1H3LMNASERPINE1 | |
| SCHEMBL3959237 | 0.73 | RORC (0.37) | TSHRMLYCDHTTMAPTLMNA | |
| SCHEMBL2749395 | 0.73 | CACNA1G (0.39) | RXRANR1H2NR1H3TSHRMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369221-B1 | Thiazolobenzoheterocycles, preparation and medicines containing same | AVENTIS PHARMA S.A. (FR) | 2002-04-09 | — | — | US | disclosed |