Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.42 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667052 | 0.91 | LTA4H (0.45) | LTA4HGAAKDM4EPOLBKCNH2 | |
| SCHEMBL7670710 | 0.90 | KDM4E (0.35) | LTA4HGAAKDM4EPOLBHRH3 | |
| SCHEMBL7670463 | 0.86 | ALDH1A1 (0.32) | — | |
| SCHEMBL7668910 | 0.85 | MEN1 (0.42) | LTA4HGAAKDM4EPOLBMEN1 | |
| SCHEMBL7664000 | 0.85 | LTA4H (0.45) | LTA4HHRH1DRD1DRD4DRD5 | |
| SCHEMBL8132685 | 0.83 | LTA4H (0.39) | LTA4HDRD1DRD4DRD5GAA | |
| SCHEMBL7666688 | 0.83 | P2RX7 (0.35) | MEN1KMT2A | |
| SCHEMBL7666718 | 0.80 | SIGMAR1 (0.43) | LTA4HGAAKDM4EPOLBKCNH2 | |
| SCHEMBL7674978 | 0.80 | ALDH1A1 (0.35) | DRD2MEN1KMT2A | |
| SCHEMBL7669032 | 0.78 | LRRK2 (0.35) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |