Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.55 |
| ▸ | TUBB | P07437 | 3/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.55 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.55 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.55 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.55 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.55 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.55 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625442 | 0.82 | TUBB1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4819729 | 0.82 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL290542 | 0.80 | LMNA (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4089388 | 0.80 | TUBB4A (0.56) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 | 0.80 | TPMT (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL27888195 | 0.80 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16677971 | 0.79 | MAPT (0.67) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL11790977 | 0.79 | MEN1 (0.57) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8148063 | 0.78 | MEN1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL11023602 | 0.78 | TPMT (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417193-B1 | ISOOXAZOLE CHLOROQUINOLONE DRUGS ANTICARCINOGENIC AGENTS AND ANTITUMOR AGENTS | ELI LILLY AND COMPANY | 2002-07-09 | — | — | US | claimed |
| EP-1069897-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 2001-01-24 | — | — | EP | claimed |
| WO-1999051227-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | claimed |
| EP-0308885-A1 | Derivatives of d-glutamic acid and d-aspartic acid | ABBOTT LABORATORIES (US) | 1989-03-29 | — | — | EP | claimed |
| WO-1989002431-A1 | DERIVATIVES OF D-GLUTAMIC ACID AND D-ASPARTIC ACID | ABBOTT LABORATORIES (US) | 1989-03-23 | — | — | WO | claimed |
| US-4610983-A | N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | claimed |
| US-6417193-B1 | ISOOXAZOLE CHLOROQUINOLONE DRUGS ANTICARCINOGENIC AGENTS AND ANTITUMOR AGENTS | ELI LILLY AND COMPANY | 2002-07-09 | — | — | US | disclosed |
| EP-1069897-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051227-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | disclosed |
| US-5128346-A | Cholecystokinin antagonists | ABBOTT LABORATORIES (US) | 1992-07-07 | — | — | US | disclosed |
| US-4971978-A | CHOLECYSTOKININ ANTAGONIST, ANALGESICS, CNS, ANALGESICS, AMIDE DERIVATIVES OF QUINOLINE | ABBOTT LABORATORIES | 1990-11-20 | — | — | US | disclosed |
| US-4906659-A | Antibiotic tan-749, its derivatives, production and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0308885-A1 | Derivatives of d-glutamic acid and d-aspartic acid | ABBOTT LABORATORIES (US) | 1989-03-29 | — | — | EP | disclosed |
| WO-1989002431-A1 | DERIVATIVES OF D-GLUTAMIC ACID AND D-ASPARTIC ACID | ABBOTT LABORATORIES (US) | 1989-03-23 | — | — | WO | disclosed |
| EP-0271829-A2 | Delta-hydroxy-beta-lysine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1988-06-22 | — | — | EP | disclosed |
| US-4610983-A | N-acyl acidic amino acid diamide derivative, a salt thereof, and an anti-ulcer agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-09 | — | — | US | disclosed |
| EP-0089926-A2 | Pharmaceutical preparations of tetracycles containing nitrogen, and compounds of this type | CIBA-GEIGY AG (CH) | 1983-09-28 | — | — | EP | disclosed |