Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 3/20 | 0.56 |
| ▸ | TUBB | P07437 | 3/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4819729 | 0.84 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4625442 | 0.84 | TUBB1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL10824650 | 0.82 | MEN1 (0.58) | TPMTCYP3A4KMT2AMEN1HTT | |
| SCHEMBL290542 | 0.82 | LMNA (0.69) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Hydrochloric Acid SCHEMBL27888195 | 0.82 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL6592 | 0.82 | TPMT (0.78) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL219096 | 0.80 | TUBB4A (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Methyl Syringate SCHEMBL211747 | 0.80 | MEN1 (0.61) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| 3,4,5-Trimethoxybenzoic Acid SCHEMBL10838612 | 0.80 | TPMT (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9968576 | 0.80 | TPMT (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239944-A1 | Novel Use of Organic Compounds | DSM IP ASSETS B.V. (NL) | 2009-09-24 | — | — | US | claimed |
| US-20090203773-A1 | Compounds for the Treatment of Non-Autoimmune Type 2 Diabetes Mellitus and/or Syndrome X | DSM IP ASSETS B.V. (NL) | 2009-08-13 | — | — | US | claimed |
| EP-1962820-A2 | MEDICAMENT FOR THE TREATMENT OF IMPAIRED GLUCOSE METABOLISM | DSMIP Assets B.V. (NL) | 2008-09-03 | — | — | EP | claimed |
| EP-1899360-A1 | COMPOUNDS FOR THE TREATMENT OF NON-AUTOIMMUNE TYPE 2 DIABETES MELLITUS AND/OR SYNDROME X | DSMIP Assets B.V. (NL) | 2008-03-19 | — | — | EP | claimed |
| WO-2006136423-A2 | MEDICAMENT FOR THE TREATMENT OF IMPAIRED GLUCOSE METABOLISM | DSM IP ASSETS B.V. (NL) | 2006-12-28 | — | — | WO | claimed |
| WO-2006136429-A1 | COMPOUNDS FOR THE TREATMENT OF NON-AUTOIMMUNE TYPE 2 DIABETES MELLITUS AND/OR SYNDROME X | DSM IP ASSETS B.V. (NL) | 2006-12-28 | — | — | WO | claimed |
| US-7122573-B2 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL (US) | 2006-10-17 | — | — | US | claimed |
| US-7109236-B2 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL (US) | 2006-09-19 | — | — | US | claimed |
| EP-1581512-A2 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | SRI INTERNATIONAL (US) | 2005-10-05 | — | — | EP | claimed |
| US-20040192723-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL | 2004-09-30 | — | — | US | claimed |
| WO-2004052873-A9 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | STANFORD RES INST INT (US) | 2004-08-12 | — | — | WO | claimed |
| WO-2004052873-A2 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | SRI INTERNATIONAL (US) | 2004-06-24 | — | — | WO | claimed |
| US-20040110790-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL | 2004-06-10 | — | — | US | claimed |
| EP-0143371-B2 | Process for the optical resolution of racemic mixtures of alpha-naphthyl-propionic acids | ALFA CHEM ITAL (IT) | 1995-11-02 | — | — | EP | claimed |
| US-4824840-A | ANTIHISTAMINES, NERVOUS SYSTEM CONTROLLERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-04-25 | — | — | US | claimed |
| US-4734416-A | ANTIHISTAMINES, CENTRAL NERVOUS SYSTEM CONTROLLING ACTION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | claimed |
| EP-0143371-B1 | PROCESS FOR THE OPTICAL RESOLUTION OF RACEMIC MIXTURES OF ALPHA-NAPHTHYL-PROPIONIC ACIDS | ALFA CHEM ITAL (IT) | 1988-02-24 | — | — | EP | claimed |
| US-4259332-A | ANTILIPEMIC, CHOLERETIC, ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | LABORATORIO CHIMICO FARMACEUTICO CAUSYTH S.P.A. (IT) | 1981-03-31 | — | — | US | claimed |
| JP-63119467-A | — | — | None | — | — | JP | disclosed |
| US-3936462-A | CNS DEPRESSANT, ANALGESIC | STERLING DRUG INC. (US) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239944-A1 | Novel Use of Organic Compounds | GPR119, IRS1, FFAR1 | TUBB4A 4847/4885TUBB 4835/4885TUBA3C 4823/4885 |
| US-20090203773-A1 | Compounds for the Treatment of Non-Autoimmune Type 2 Diabetes Mellitus and/or Syndrome X | GPR119, HRH3, ARG2 | TUBB4A 2992/4885TUBB 3377/4885TUBA3C 2394/4885 |
| US-20040192723-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | TEAD4, TEAD3, TEAD1 | TUBB4A 348/4885TUBB 562/4885TUBA3C 458/4885 |
| US-20040110790-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | TEAD4, TEAD3, TEAD1 | TUBB4A 348/4885TUBB 562/4885TUBA3C 458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.