Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787083 | 0.85 | ADORA3 (0.47) | ADORA3ADORA2AADORA1TP53PAK1 | |
| SCHEMBL767164 | 0.76 | HPGDS (0.42) | MAP4K4TP53PAK1MAPTIRAK4 | |
| SCHEMBL31038592 | 0.72 | KMT2A (0.41) | TP53MAPTUSP2CYP1A2MAPK1 | |
| SCHEMBL31038591 | 0.72 | KMT2A (0.41) | TP53MAPTUSP2CYP1A2MAPK1 | |
| SCHEMBL4353155 | 0.71 | MAP4K4 (0.79) | MAP4K4IRAK4USP2CYP1A2CYP3A4 | |
| SCHEMBL21138338 | 0.70 | HPGDS (0.47) | MAP4K4ADORA1TP53PAK1HPGDS | |
| SCHEMBL30808262 | 0.70 | HPGDS (0.47) | MAP4K4ADORA1TP53PAK1HPGDS | |
| SCHEMBL21138485 | 0.70 | CD38 (0.40) | MAP4K4IRAK4HPGDSCYP3A4 | |
| SCHEMBL28890932 | 0.69 | HPGDS (0.42) | MAP4K4PAK1IRAK4HPGDSCYP3A4 | |
| SCHEMBL11617161 | 0.69 | HPGDS (0.50) | ADORA1TP53PAK1MAPTHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102395570-B | Aminopyrimidinamides as pest control agents | BAYER CROPSCIENCE AG | 2015-01-21 | — | — | CN | disclosed |
| EP-2398778-B1 | AMINOPYRIDINEAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2398778-B1 | AMINOPYRIDINEAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| EP-2398778-A1 | AMINOPYRIMIDINAMIDES AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2011-12-28 | — | — | EP | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2246335-A1 | Aminopyridineamides as pesticides | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| EP-2246335-A1 | Aminopyridineamides as pesticides | Bayer CropScience AG (DE) | 2010-11-03 | — | — | EP | disclosed |
| WO-2010094406-A1 | AMINOPYRIMIDINAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010094406-A1 | AMINOPYRIMIDINAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | DDT, NPEPPS, PTMS | MAP4K4 1859/4885ADORA3 3147/4885ADORA2A 3520/4885 |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | NPEPPS, DDT, DNPEP | MAP4K4 1020/4885ADORA3 4231/4885ADORA2A 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.