Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681550 | 0.84 | APLNR (0.41) | ALDH1A1HPGDRAB9ANPC1ATM | |
| SCHEMBL7679216 | 0.83 | TP53 (0.33) | MAPTTP53 | |
| SCHEMBL6678132 | 0.82 | OXTR (0.41) | ALDH1A1HPGDAPLNRTSHRHTT | |
| SCHEMBL7676180 | 0.79 | ACHE (0.40) | ALDH1A1HPGDRAB9ANPC1MAPT | |
| SCHEMBL7674184 | 0.78 | SLC2A1 (0.37) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL7673152 | 0.78 | CYP11B2 (0.38) | ALDH1A1HPGDRAB9ANPC1ATM | |
| SCHEMBL7677312 | 0.75 | OXTR (0.41) | ALDH1A1HPGDAPLNRTSHRHTT | |
| SCHEMBL7676400 | 0.75 | OXTR (0.41) | ALDH1A1HPGDAPLNRTSHRHTT | |
| SCHEMBL7682758 | 0.73 | CYP11B2 (0.46) | ALDH1A1HPGDRAB9ANPC1ATM | |
| SCHEMBL27502563 | 0.72 | APLNR (0.43) | ALDH1A1HPGDRAB9ANPC1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376490-B1 | STRONG N-METHYL-D-ASPARATE RECEPTOR ANTAGONISTS; USEFUL IN TREATING STROKES, ISCHEMIA, AND CENTRAL NERVOUS SYSTEM INJURIES | PFIZER INC | 2002-04-23 | — | — | US | disclosed |
| EP-0885212-B1 | QUINOXALINEDIONES | PFIZER RES AND BR DEV COMPANY (IE) | 2001-11-14 | — | — | EP | disclosed |