Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SGK1 | O00141 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664213 | 0.89 | KIF11 (0.36) | KIF11LOXL2 | |
| SCHEMBL7663652 | 0.85 | — | — | |
| SCHEMBL7666295 | 0.81 | OPRD1 (0.38) | KIF11 | |
| SCHEMBL7668534 | 0.80 | ALDH1A1 (0.34) | — | |
| SCHEMBL5891827 | 0.79 | CYP19A1 (0.36) | KIF11MAOB | |
| SCHEMBL7671110 | 0.75 | KDM4E (0.40) | SGK1 | |
| SCHEMBL7669882 | 0.73 | VNN1 (0.35) | KIF11MAOB | |
| SCHEMBL8149150 | 0.73 | NR3C1 (0.35) | MAOB | |
| SCHEMBL7668479 | 0.71 | CA12 (0.58) | — | |
| SCHEMBL6775340 | 0.71 | BRS3 (0.33) | SGK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407132-B1 | ANTIHISTAMINES, ANTIALLERGENS, ANTIASTHMATICS, ANTICONVULSANTS, AND ANTIDEPRESSANTS; SKIN RASH TREATMENT | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-06-18 | — | — | US | disclosed |