Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15887427 | 0.79 | SORD (0.51) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2320496 | 0.77 | SORD (0.51) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL31014265 | 0.77 | SORD (0.51) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL18228513 | 0.77 | SORD (0.51) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2074813 | 0.76 | LMNA (0.54) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL2074811 | 0.76 | SORD (0.51) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7678393 | 0.75 | L3MBTL1 (0.50) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5525542 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1 | |
| SCHEMBL27723124 | 0.75 | SLC6A7 (0.59) | SORDKDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL468382 | 0.75 | SORD (0.50) | SORDKDM4ELMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |