Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.39 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682738 | 0.92 | ALDH1A1 (0.37) | PDE4BPDE4DPDE4APDE4CP2RX7 | |
| SCHEMBL7677539 | 0.89 | HPGD (0.39) | PDE4BPDE4DPDE4APDE4CP2RX7 | |
| SCHEMBL7678830 | 0.88 | PDE4A (0.33) | PDE4BPDE4DPDE4APDE4CPTGER4 | |
| SCHEMBL7679361 | 0.86 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CPTGES | |
| SCHEMBL7681363 | 0.84 | PTGS2 (0.41) | PDE4BPDE4DPDE4APDE4CS1PR4 | |
| SCHEMBL7677645 | 0.84 | PTGS2 (0.40) | PDE4BPDE4DPDE4APDE4CPTGS2 | |
| SCHEMBL7677655 | 0.84 | CNR2 (0.40) | PDE4BPDE4DPDE4APDE4CP2RX7 | |
| SCHEMBL7684085 | 0.83 | PDE4D (0.40) | PDE4BPDE4DPDE4APDE4CPTGER4 | |
| SCHEMBL7677560 | 0.81 | GRM5 (0.35) | PDE4BPDE4DPDE4APDE4CL3MBTL1 | |
| SCHEMBL7682639 | 0.77 | ALDH1A1 (0.38) | PDE4BPDE4DPDE4APDE4CSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472349-B1 | Pyridine-2,3-dicarboxylic acid diamides | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-29 | — | — | US | claimed |