Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 12/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683405 | 0.91 | KIF11 (0.38) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL7855705 | 0.88 | SIRT1 (0.45) | LMNAMAPTSIRT1KIF11TP53 | |
| SCHEMBL7680170 | 0.87 | LMNA (0.52) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7693228 | 0.87 | MEN1 (0.48) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7681633 | 0.87 | MEN1 (0.48) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7680379 | 0.86 | MAPT (0.51) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7683791 | 0.85 | SIRT1 (0.56) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7677069 | 0.85 | MEN1 (0.49) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7683286 | 0.85 | DHODH (0.49) | LMNAMAPTMEN1KMT2ASIRT1 | |
| SCHEMBL7684013 | 0.85 | MAPT (0.51) | LMNAMAPTMEN1KMT2ASIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |