Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678448 | 0.89 | HPGD (0.47) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL2487391 | 0.82 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL2789494 | 0.78 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL2892926 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL21801994 | 0.72 | — | — | |
| SCHEMBL437231 | 0.71 | ALDH1A1 (0.87) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL7680902 | 0.70 | BCAT2 (0.40) | NPC1RAB9ABCAT2 | |
| SCHEMBL1991348 | 0.69 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL45299 | 0.69 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AHPGDHTT | |
| SCHEMBL11266257 | 0.69 | ALDH1A1 (0.83) | ALDH1A1MEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369088-B2 | ANTIDIABETIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |