Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680897 | 0.89 | ALDH1A1 (0.51) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2487391 | 0.74 | ALDH1A1 (0.47) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4138863 | 0.71 | HPGD (0.77) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2789494 | 0.70 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL22396430 | 0.69 | ALDH1A1 (0.38) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL18190481 | 0.68 | MEN1 (0.72) | HPGDALDH1A1MEN1KMT2AGFER | |
| SCHEMBL7680902 | 0.68 | BCAT2 (0.40) | NPC1RAB9ABCAT2 | |
| SCHEMBL28244196 | 0.67 | HPGD (0.60) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL437231 | 0.66 | ALDH1A1 (0.87) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5229927 | 0.66 | KCNK3 (0.68) | HPGDALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6369088-B2 | ANTIDIABETIC AGENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-04-09 | — | — | US | disclosed |