Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 2/20 | 0.40 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ERG | P11308 | 1/20 | 0.35 |
| ▸ | HAT1 | O14929 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BRS3 | P32247 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180669 | 0.83 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL6215244 | 0.74 | FNTA (0.40) | FNTAFNTBALDH1A1 | |
| SCHEMBL7841490 | 0.72 | CHRM4 (0.54) | GPBAR1ERGEP300BRS3 | |
| Hydrochloric Acid SCHEMBL7845666 | 0.71 | CHRM4 (0.53) | GPBAR1ERGEP300BRS3 | |
| SCHEMBL7459728 | 0.70 | FNTA (0.42) | FNTAFNTBPRKAA2GPBAR1CYP3A4 | |
| Hydrochloric Acid SCHEMBL7452346 | 0.70 | FNTA (0.42) | FNTAFNTBPRKAA2GPBAR1CYP3A4 | |
| SCHEMBL6178566 | 0.68 | FNTA (0.42) | FNTAFNTBALDH1A1CYP3A4CNR1 | |
| SCHEMBL7679202 | 0.68 | FNTA (0.48) | FNTAFNTBPRKAA2ALDH1A1 | |
| SCHEMBL6179814 | 0.67 | FNTA (0.46) | FNTAFNTB | |
| SCHEMBL2226022 | 0.67 | FNTA (0.44) | FNTAFNTBALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |