Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.42 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689106 | 0.85 | KDM1A (0.46) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL7687546 | 0.81 | LMNA (0.57) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL7683566 | 0.79 | GAA (0.54) | LMNAHTTSIGMAR1ALDH1A1GAA | |
| SCHEMBL5873672 | 0.78 | GAA (0.55) | LMNAHTTSIGMAR1ALDH1A1GAA | |
| SCHEMBL24239933 | 0.77 | ALDH1A1 (0.58) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL7315510 | 0.76 | KDM1A (0.67) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL8395178 | 0.74 | PARP1 (0.51) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL8207009 | 0.74 | SIGMAR1 (0.43) | PARP1SIGMAR1TGM2GAA | |
| SCHEMBL7758912 | 0.73 | KDM1A (0.64) | KDM1ARCOR1LMNAHTTNPSR1 | |
| SCHEMBL7458364 | 0.73 | ALDH1A1 (0.65) | KDM1ARCOR1LMNAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868202-B1 | CASCADE POLYMER COMPLEXES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICALS CONTAINING THE SAME | SCHERING AG (DE) | 2002-08-28 | — | — | EP | disclosed |
| US-6057419-A | DRUGS AND IMAGES | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |
| US-5874061-A | PARAMAGNETIC CONTRAST AGENTS FOR BOTH NUCLEAR SPIN AND COMPUTOR TOMOGRAPHY AND MAGNETIC RESONANCE IMAGING; MARKING VASCULAR SPACE (BLOOD-POOL AGENTS); BIOCOMPATIBILITY; HIGH SIGNAL INTENSITY, THEREFORE A LOWER DOSAGE USED | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |