Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7689241 | 0.84 | HCAR2 (0.48) | MAP1LC3BHTR2CLMNATSHRPKM | |
| SCHEMBL7682852 | 0.82 | HSD17B10 (0.39) | LMNATSHRPKMHTTTP53 | |
| SCHEMBL7683237 | 0.82 | SMN1; SMN2 (0.48) | MAP1LC3BADRA1ALMNATSHRPKM | |
| Hydrochloric Acid SCHEMBL7686909 | 0.74 | ADRA1D (0.36) | MAP1LC3BADRA1AADRA1DHTR2CLMNA | |
| SCHEMBL1779006 | 0.73 | HSP90AA1 (0.66) | MAP1LC3BLMNATSHRPKMHTT | |
| SCHEMBL7683944 | 0.72 | MAP1LC3B (0.53) | MAP1LC3BADRA1AADRA1D | |
| SCHEMBL7689368 | 0.72 | PIM1 (0.45) | MAP1LC3BLMNATSHRPKMHTT | |
| Hydrochloric Acid SCHEMBL7687660 | 0.72 | PIM1 (0.44) | MAP1LC3BLMNATSHRPKMHTT | |
| SCHEMBL7680888 | 0.71 | MAP1LC3B (0.51) | MAP1LC3BHTR2CLMNAPKMMEN1 | |
| SCHEMBL6922001 | 0.70 | PKM (0.58) | MAP1LC3BADRA1AADRA1DHTR2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |