SCHEMBL7684500

SCHEMBL7684500

Cn1nc(-c2ncc(Cl)cc2F)c(Cl)c1OC(F)F

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC34A1 Q06495 2/20 0.34
FPR2 P25090 1/20 0.33
PROKR1 Q8TCW9 1/20 0.33
PDE2A O00408 1/20 0.32
RXRA P19793 2/20 0.31
GRIN1 Q05586 2/20 0.31
GRIN2B Q13224 2/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LMNA P02545 1/20 0.30
PABPC1 P11940 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7691222 0.90 SLC34A1 (0.32) SLC34A1PDE2ARXRAGRIN1GRIN2B
SCHEMBL7906774 0.87 KCNH2 (0.33) SLC34A1FPR2PROKR1PDE2ARXRA
SCHEMBL7904399 0.87 FPR2 (0.32) SLC34A1FPR2PROKR1PDE2A
SCHEMBL7691034 0.87 FPR2 (0.32) SLC34A1FPR2PROKR1PDE2A
SCHEMBL7689593 0.84 SMN1; SMN2 (0.38) FPR2PROKR1PDE2ASMN1; SMN2HPGD
SCHEMBL7898138 0.82 MAPT (0.35) SLC34A1FPR2PROKR1MAPTLMNA
SCHEMBL7907743 0.80 LMNA (0.31) SLC34A1KMT2ALMNA
SCHEMBL6295365 0.79 HSD11B1 (0.36) SLC34A1FPR2PROKR1PDE2AMEN1
SCHEMBL7685933 0.79 SLC34A1 (0.32) SLC34A1
SCHEMBL7684721 0.77 SLC34A1 (0.31) SLC34A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020055639-A1 Pyrazole derivatives as herbicides NEBEL KURT (CH) 2002-05-09 US disclosed
US-6274536-B1 CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE SYNGENTA CROP PROTECTION, INC. 2001-08-14 US disclosed
US-6204221-B1 Herbicides SYNGENTA CROP PROTECTION, INC. 2001-03-20 US disclosed
CN-1250446-A Pyrazole derivatives as herbicides NOVARTIS AG (CH) 2000-04-12 CN disclosed
EP-0966461-A1 PYRAZOLE DERIVATIVES AS HERBICIDES Novartis AG (CH) 1999-12-29 EP disclosed
CN-1237166-A Pyrazole derivatives useful as herbicides NOVARTIS AG (CH) 1999-12-01 CN disclosed
EP-0941222-A2 PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES Novartis AG (CH) 1999-09-15 EP disclosed
WO-1998042698-A1 PYRAZOLE DERIVATIVES AS HERBICIDES NOVARTIS AG (CH) 1998-10-01 WO disclosed
WO-1998021199-A2 PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES NOVARTIS AG (CH) 1998-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020055639-A1 Pyrazole derivatives as herbicides CBR3, HCN1, HCN2 SLC34A1 2631/4885FPR2 1791/4885PROKR1 1612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.