Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684500 | 0.84 | SLC34A1 (0.34) | SMN1; SMN2FPR2PROKR1PDE2AHPGD | |
| SCHEMBL7904399 | 0.82 | FPR2 (0.32) | FPR2PROKR1PDE2A | |
| SCHEMBL7906774 | 0.82 | KCNH2 (0.33) | FPR2PROKR1PDE2A | |
| SCHEMBL7691034 | 0.82 | FPR2 (0.32) | FPR2PROKR1PDE2A | |
| SCHEMBL7898138 | 0.80 | MAPT (0.35) | CYP1A2CYP2C9CYP2C19FPR2PROKR1 | |
| SCHEMBL7691222 | 0.74 | SLC34A1 (0.32) | PDE2A | |
| SCHEMBL7691458 | 0.72 | FPR2 (0.33) | SMN1; SMN2FPR2PROKR1PDE2A | |
| SCHEMBL7907720 | 0.71 | FPR2 (0.37) | FPR2PROKR1PDE2ASMOHPGD | |
| SCHEMBL7906751 | 0.70 | CYP1A2 (0.31) | SMN1; SMN2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7907722 | 0.69 | FPR2 (0.33) | FPR2PROKR1PDE2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020055639-A1 | Pyrazole derivatives as herbicides | NEBEL KURT (CH) | 2002-05-09 | — | — | US | disclosed |
| US-6274536-B1 | CROPS, AGRICULTURE; PRE- AND POSTEMERGENCE | SYNGENTA CROP PROTECTION, INC. | 2001-08-14 | — | — | US | disclosed |
| US-6204221-B1 | Herbicides | SYNGENTA CROP PROTECTION, INC. | 2001-03-20 | — | — | US | disclosed |
| EP-0966461-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | Novartis AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| EP-0941222-A2 | PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | Novartis AG (CH) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998042698-A1 | PYRAZOLE DERIVATIVES AS HERBICIDES | NOVARTIS AG (CH) | 1998-10-01 | — | — | WO | disclosed |
| WO-1998021199-A2 | PYRAZOLE DERIVATIVES USEFUL AS HERBICIDES | NOVARTIS AG (CH) | 1998-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020055639-A1 | Pyrazole derivatives as herbicides | CBR3, HCN1, HCN2 | SMN1; SMN2 3144/4885CYP1A2 442/4885CYP2C9 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.