Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CTSV | O60911 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686728 | 0.86 | HPGD (0.62) | L3MBTL1HPGDALOX12CTSVCTSL | |
| SCHEMBL11126171 | 0.80 | CNR1 (0.62) | CNR1CNR2MAPTKMT2AMEN1 | |
| SCHEMBL7919851 | 0.79 | CNR1 (0.55) | CNR1CNR2MAPTKMT2AMEN1 | |
| SCHEMBL11828315 | 0.74 | GAA (0.44) | L3MBTL1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL7165547 | 0.70 | L3MBTL1 (0.57) | L3MBTL1HPGDALOX12CTSVCTSL | |
| SCHEMBL8646829 | 0.69 | ALDH1A1 (0.46) | CNR1CNR2MAPTKMT2AMEN1 | |
| SCHEMBL9871987 | 0.69 | ALDH1A1 (0.47) | L3MBTL1CNR1CNR2MAPTKMT2A | |
| SCHEMBL10347131 | 0.69 | CYP3A4 (0.48) | HPGDCNR1CNR2MAPTKMT2A | |
| SCHEMBL7686731 | 0.68 | HPGD (0.57) | L3MBTL1HPGDALOX12CNR1CNR2 | |
| SCHEMBL4251354 | 0.68 | CTSV (0.71) | L3MBTL1HPGDALOX12CTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482822-B1 | N-(iminomethyl)amines derivatives, their preparation, their use as medicines and compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-11-19 | — | — | US | disclosed |