Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126171 | 0.89 | CNR1 (0.62) | CNR1CNR2MEN1KMT2AMAPT | |
| SCHEMBL7919851 | 0.87 | CNR1 (0.55) | CNR1CNR2MEN1KMT2AMAPT | |
| SCHEMBL7686726 | 0.86 | L3MBTL1 (0.48) | HPGDALOX12L3MBTL1CNR1CNR2 | |
| SCHEMBL224794 | 0.79 | ALOX12 (1.00) | HPGDALOX12L3MBTL1CXCR2MEN1 | |
| SCHEMBL9479463 | 0.79 | ALOX12 (1.00) | HPGDALOX12L3MBTL1CXCR2MEN1 | |
| SCHEMBL7686731 | 0.78 | HPGD (0.57) | HPGDALOX12L3MBTL1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL3693418 | 0.77 | ALOX12 (0.96) | HPGDALOX12L3MBTL1CXCR2MEN1 | |
| SCHEMBL9717470 | 0.77 | ALOX12 (0.96) | HPGDALOX12L3MBTL1CXCR2MEN1 | |
| SCHEMBL8646829 | 0.77 | ALDH1A1 (0.46) | CNR1CNR2MEN1KMT2AMAPT | |
| SCHEMBL11824779 | 0.75 | LTA4H (0.48) | HPGDALOX12L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482822-B1 | N-(iminomethyl)amines derivatives, their preparation, their use as medicines and compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-11-19 | — | — | US | disclosed |