Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686728 | 0.78 | HPGD (0.62) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL3097653 | 0.76 | TSHR (0.61) | MEN1KMT2AMAPTALDH1A1ANPEP | |
| SCHEMBL8474950 | 0.76 | NOS2 (0.50) | HPGDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL224794 | 0.76 | ALOX12 (1.00) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL9479463 | 0.76 | ALOX12 (1.00) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL6810144 | 0.76 | KMT2A (0.52) | MEN1KMT2AMAPTPTPRFPTPN2 | |
| SCHEMBL6810226 | 0.76 | KMT2A (0.52) | MEN1KMT2AMAPTPTPRFPTPN2 | |
| SCHEMBL7429456 | 0.76 | NPC1 (0.53) | MEN1KMT2AMAPTALDH1A1ANPEP | |
| SCHEMBL4659127 | 0.75 | CNR1 (0.73) | HPGDALOX12L3MBTL1MEN1KMT2A | |
| SCHEMBL4627177 | 0.75 | KMT2A (0.68) | HPGDALOX12L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482822-B1 | N-(iminomethyl)amines derivatives, their preparation, their use as medicines and compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-11-19 | — | — | US | disclosed |