Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 13/20 | 0.68 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | BRD2 | P25440 | 2/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770387 | 0.81 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL6770069 | 0.65 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL27545111 | 0.61 | PGR (0.71) | PGRNR3C1NR3C2AR | |
| SCHEMBL3872257 | 0.58 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL3135050 | 0.57 | ALOX15 (0.55) | PGRNR3C1NR3C2ARBRD4 | |
| SCHEMBL27475124 | 0.57 | PGR (0.60) | PGRNR3C1NR3C2AR | |
| SCHEMBL6769679 | 0.57 | PGR (0.98) | PGRNR3C1NR3C2AR | |
| SCHEMBL6772265 | 0.57 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL6770186 | 0.57 | PGR (1.00) | PGRNR3C1NR3C2AR | |
| SCHEMBL27340100 | 0.56 | PTGS2 (0.45) | PGRNR3C1NR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175404-A1 | QUINAZOLINONE AND BENZOXAZINE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | American Home Products Corporation (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066560-A1 | QUINAZOLINONE AND BENZOXAZINE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | disclosed |