SCHEMBL7907720

SCHEMBL7907720

COS(=O)(=O)Oc1c(C)c(-c2ncc(Cl)cc2F)nn1C

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.37
PROKR1 Q8TCW9 4/20 0.37
GRM5 P41594 2/20 0.35
SMO Q99835 1/20 0.34
HTT P42858 2/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PTGS2 P35354 7/20 0.32
PTGS1 P23219 3/20 0.32
ABCC4 O15439 1/20 0.31
ABCB11 O95342 1/20 0.31
PDE4D Q08499 1/20 0.31
MAPK14 Q16539 1/20 0.31
PDE2A O00408 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
PABPC1 P11940 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7907722 0.78 FPR2 (0.33) FPR2PROKR1GRM5HTTHPGD
SCHEMBL7904400 0.76 SMO (0.39) FPR2PROKR1GRM5SMOHTT
SCHEMBL7910781 0.73 GRM5 (0.39) FPR2PROKR1GRM5SMOMEN1
SCHEMBL7910810 0.71 KMT2A (0.38) FPR2PROKR1GRM5SMOHTT
SCHEMBL7688652 0.71 GRM5 (0.38) FPR2PROKR1GRM5SMOHTT
SCHEMBL7689593 0.71 SMN1; SMN2 (0.38) FPR2PROKR1SMOHTTHPGD
SCHEMBL7687299 0.70 GRM5 (0.35) FPR2PROKR1GRM5SMOHTT
SCHEMBL7684500 0.70 SLC34A1 (0.34) FPR2PROKR1HTTHPGDHSD17B10
SCHEMBL7687213 0.70 HTR5A (0.38) FPR2PROKR1GRM5SMOHTT
SCHEMBL7690463 0.69 TGFBR1 (0.34) FPR2PROKR1GRM5SMOHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204221-B1 Herbicides SYNGENTA CROP PROTECTION, INC. 2001-03-20 US disclosed