SCHEMBL7907722

SCHEMBL7907722

CSOc1c(C)c(-c2ncc(Cl)cc2F)nn1C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.33
PROKR1 Q8TCW9 1/20 0.33
PDE2A O00408 1/20 0.32
GRM5 P41594 2/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30
PABPC1 P11940 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7687299 0.80 GRM5 (0.35) FPR2PROKR1PDE2AGRM5HPGD
SCHEMBL7907720 0.78 FPR2 (0.37) FPR2PROKR1PDE2AGRM5HPGD
SCHEMBL7684500 0.74 SLC34A1 (0.34) FPR2PROKR1PDE2AHPGDHTT
SCHEMBL7690463 0.73 TGFBR1 (0.34) FPR2PROKR1PDE2AGRM5HPGD
SCHEMBL7910810 0.72 KMT2A (0.38) FPR2PROKR1PDE2AGRM5HPGD
SCHEMBL7904400 0.72 SMO (0.39) FPR2PROKR1PDE2AGRM5HPGD
SCHEMBL7688652 0.72 GRM5 (0.38) FPR2PROKR1PDE2AGRM5HPGD
SCHEMBL7910781 0.72 GRM5 (0.39) FPR2PROKR1GRM5MEN1KMT2A
SCHEMBL7691034 0.72 FPR2 (0.32) FPR2PROKR1PDE2A
SCHEMBL7904399 0.72 FPR2 (0.32) FPR2PROKR1PDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204221-B1 Herbicides SYNGENTA CROP PROTECTION, INC. 2001-03-20 US disclosed