SCHEMBL6243131

SCHEMBL6243131

CCCCCOC1=NS(=O)(=O)c2ccccc21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.72
RAB9A P51151 1/20 0.55
ALDH1A1 P00352 3/20 0.53
GAA P10253 3/20 0.51
HSD17B10 Q99714 3/20 0.51
HTT P42858 1/20 0.51
LMNA P02545 1/20 0.51
KDM4E B2RXH2 2/20 0.48
THRB P10828 1/20 0.48
ALOX15 P16050 1/20 0.48
RECQL P46063 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MAPT P10636 3/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KCNA3 P22001 3/20 0.43
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
HPGD P15428 1/20 0.41
PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6910103 0.91 PKM (0.77) PKMRAB9AALDH1A1GAAHSD17B10
SCHEMBL8437480 0.84 PKM (1.00) PKMRAB9AALDH1A1GAAHSD17B10
SCHEMBL8439404 0.81 PKM (0.66) PKMRAB9AALDH1A1GAAHSD17B10
SCHEMBL11024449 0.75 HSD17B10 (0.71) PKMALDH1A1GAAHSD17B10HTT
SCHEMBL7693631 0.75 PKM (0.50) PKMRAB9AALDH1A1GAAHSD17B10
SCHEMBL7738030 0.75 ALDH1A1 (0.79) PKMRAB9AALDH1A1GAAHSD17B10
Probenazol SCHEMBL8409812 0.74 PKM (0.65) PKMRAB9AALDH1A1GAAHSD17B10
Probenazol SCHEMBL30425932 0.74 PKM (0.65) PKMRAB9AALDH1A1GAAHSD17B10
SCHEMBL3169857 0.70 KDM4E (0.46) PKMRAB9AALDH1A1GAALMNA
SCHEMBL20567484 0.69 PKM (0.54) PKMRAB9AALDH1A1GAAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1148107-B1 COATED BIOLOGICALLY ACTIVE GRAINS CHISSO CORP (JP) 2005-03-02 EP disclosed
EP-1148107-A1 COATED BIOLOGICALLY ACTIVE GRAINS Chisso Corporation (JP) 2001-10-24 EP disclosed