Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 10/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8436388 | 0.83 | KCNA3 (0.63) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL8435929 | 0.74 | KCNA3 (0.64) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL7693631 | 0.74 | PKM (0.50) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL8956475 | 0.72 | PKM (0.51) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL6243131 | 0.72 | PKM (0.72) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL20529368 | 0.71 | KCNA3 (0.60) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL4393225 | 0.71 | KCNA3 (0.59) | KCNA3PKMLMNAALDH1A1GAA | |
| SCHEMBL3853334 | 0.71 | MAPT (0.51) | PKMLMNAALDH1A1GAANPC1 | |
| Cetrimonium SCHEMBL29623712 | 0.70 | PKM (0.43) | KCNA3PKMALDH1A1GAAHTT | |
| SCHEMBL20567484 | 0.68 | PKM (0.54) | KCNA3PKMLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |