Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.44 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL635580 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL2979400 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL678415 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL362235 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL164301 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL7759526 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL1866839 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL286882 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL8775234 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL2446607 | 0.98 | HIF1A (0.56) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894562-B | Zero-dimensional hybridization cuprous halide material with photoluminescence and radiation luminescence properties, and preparation method and application thereof | 济宁学院 | 2024-08-20 | — | — | CN | claimed |
| CN-118209650-A | Method for extracting and determining succinate dehydrogenase inhibitor based on magnetic eutectic solvent-liquid microextraction-high performance liquid chromatography | 山西农业大学 | 2024-06-18 | — | — | CN | claimed |
| CN-115894562-A | Zero-dimensional hybridized cuprous halide material with excellent photoluminescence and radiation luminescence properties and preparation method and application thereof | 济宁学院 | 2023-04-04 | — | — | CN | claimed |
| CN-114634528-A | Efficient narrow-band green light emitting metal halide and preparation method and application thereof | 华南理工大学 | 2022-06-17 | — | — | CN | claimed |
| CN-114214031-A | Flame-retardant polyphenyl ether adhesive and preparation method and application thereof | 四川大学 | 2022-03-22 | — | — | CN | claimed |
| CN-110283304-B | Dithienobenzene diimide-based conjugated polymer and preparation method and application thereof | 南京邮电大学 | 2021-12-28 | — | — | CN | claimed |
| CN-110143968-B | Dithienophenyldiimide derivative and preparation method and application thereof | 南京邮电大学 | 2020-12-01 | — | — | CN | claimed |
| CN-111943820-A | Method for simply and efficiently synthesizing alpha, beta-unsaturated aldehyde without synthesis gas | 四川大学 | 2020-11-17 | — | — | CN | claimed |
| CN-111825537-A | Method for efficiently synthesizing alpha, beta-unsaturated aldehyde without synthesis gas | 四川大学 | 2020-10-27 | — | — | CN | claimed |
| CN-110283304-A | A kind of Dithiophene acene imidodicarbonic diamide base conjugated polymer and the preparation method and application thereof | 南京邮电大学 | 2019-09-27 | — | — | CN | claimed |
| US-20170129874-A1 | NOVEL IMPROVED PROCESS FOR PREPARING A TRIAZOLE ANTIFUNGAL AGENT | VIRUPAKSHA ORGANICS LTD (IN) | 2017-05-11 | — | — | US | claimed |
| US-7709168-B2 | Phosphonium containing charge transport layer photoconductors | XEROX CORPORATION (US) | 2010-05-04 | — | — | US | claimed |
| US-20090092914-A1 | PHOSPHONIUM CONTAINING PHOTOGENERATING LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| US-20090092915-A1 | PHOSPHONIUM CONTAINING CHARGE TRANSPORT LAYER PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2009-04-09 | — | — | US | claimed |
| US-6248161-B1 | Preparation of permanent color inks from water-soluble colorants using specific phosphonium salts | HEWLETT-PACKARD COMPANY | 2001-06-19 | — | — | US | claimed |
| WO-1996007707-A1 | EPOXY RESIN POWDER COATING COMPOSITION | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1996-03-14 | — | — | WO | claimed |
| EP-0181568-A2 | Anti-inflammatory/anti-allergic compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1986-05-21 | — | — | EP | claimed |
| US-20260144251-A1 | ANTIMICROBIAL NANOCLAYS COMPRISING CATIONIC ANTIMICROBIALS, METHOD OF PREPARATION AND USES THEREOF | POLYAMYNA NANOTECH INC. (CA) | 2026-05-28 | — | — | US | disclosed |
| US-3987073-A | SYNTHESIS OF TRIDECADIENOIC ESTERS | ZOECON CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |
| US-3953532-A | 4,8-Tridecadien-1-ol,4 cis,8 cis,trans | ZOECON CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260144251-A1 | ANTIMICROBIAL NANOCLAYS COMPRISING CATIONIC ANTIMICROBIALS, METHOD OF PREPARATION AND USES THEREOF | KLF10, SLC11A2, SLC7A11 | HIF1A 3809/4885ALDH1A1 4757/4885CYP1A2 4682/4885 |
| US-20170129874-A1 | NOVEL IMPROVED PROCESS FOR PREPARING A TRIAZOLE ANTIFUNGAL AGENT | ERG28, CYP51A1, CYP4F11 | HIF1A 1790/4885ALDH1A1 3171/4885CYP1A2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.