Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 2/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690063 | 0.90 | LMNA (0.37) | LMNARAPGEF4CA2CA12MMP2 | |
| SCHEMBL7693707 | 0.88 | LMNA (0.42) | LMNARAPGEF4CA2CA12MMP2 | |
| SCHEMBL7693043 | 0.88 | MMP2 (0.42) | CA2CA12MMP2MMP9MMP14 | |
| SCHEMBL7720645 | 0.85 | KMT2A (0.41) | LMNARAPGEF4RAPGEF3MEP1BTDP1 | |
| SCHEMBL7690154 | 0.85 | MMP2 (0.46) | LMNACA2CA12MMP2MMP9 | |
| SCHEMBL7721788 | 0.82 | MAPT (0.44) | LMNARAPGEF3POLBKMT2ANPC1 | |
| SCHEMBL6741894 | 0.82 | PDIA6 (0.41) | CA2CA12MMP9NPC1 | |
| SCHEMBL6737115 | 0.82 | PDIA6 (0.41) | CA2CA12MMP9NPC1 | |
| SCHEMBL36946 | 0.81 | RAPGEF4 (0.44) | LMNARAPGEF4MEP1BPOLBHTT | |
| SCHEMBL29362738 | 0.81 | RAPGEF4 (0.44) | LMNARAPGEF4MEP1BPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6338931-B1 | PHOTOACID GENERATOR OF SULFONYLDIAZOMETHANE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-01-15 | — | — | US | disclosed |