Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696209 | 0.86 | KDM4E (0.55) | MAPTTP53THRBALDH1A1KDM4E | |
| SCHEMBL7695770 | 0.84 | MAPT (0.58) | MAPTTP53THRBALDH1A1KDM4E | |
| SCHEMBL7704976 | 0.83 | MAPT (0.61) | MAPTTP53THRBALDH1A1KDM4E | |
| SCHEMBL7698148 | 0.81 | PTGES (0.49) | MAPTTP53THRBALDH1A1KDM4E | |
| SCHEMBL7701897 | 0.81 | KDM4E (0.55) | MAPTALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL7693588 | 0.81 | KDM4E (0.65) | MAPTTP53ALDH1A1KDM4ERAB9A | |
| SCHEMBL7701071 | 0.81 | TSHR (0.63) | MAPTTP53THRBALDH1A1KDM4E | |
| SCHEMBL7698787 | 0.79 | KDM4E (0.58) | MAPTTP53ALDH1A1KDM4ERAB9A | |
| SCHEMBL7698683 | 0.79 | MAPT (0.52) | MAPTTP53ALDH1A1KDM4ERAB9A | |
| SCHEMBL7695319 | 0.79 | MAPT (0.57) | MAPTTP53ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |