Methylamine

Methylamine

SCHEMBL769652

CCOC(CC)C(N)C(CC)OCC.CN

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27471022 0.78 LMNA (0.56) LMNATHRB
SCHEMBL28099090 0.78 LMNA (0.43) LMNATHRB
SCHEMBL7260913 0.71
SCHEMBL9546948 0.70 LMNA (0.42) LMNATHRB
SCHEMBL12514138 0.69 LMNA (0.45) LMNATHRB
SCHEMBL309862 0.67
SCHEMBL29012739 0.67 LMNA (0.50) LMNATHRB
SCHEMBL20886292 0.67 LMNA (0.50) LMNATHRB
SCHEMBL29012741 0.67 LMNA (0.50) LMNATHRB
SCHEMBL27803885 0.67 THRB (0.44) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2438038-B1 PROCESS FOR THE PREPARATION OF SECONDARY OR TERTIARY AMINES HUNTSMAN CORP HUNGARY ZRT (HU) 2016-04-20 EP disclosed
US-8822729-B2 Method for providing a secondary or tertiary amine HUNTSMAN INTERNATIONAL LLC (US) 2014-09-02 US disclosed
US-20140155655-A1 Method for providing a secondary or tertiary amine Huntsman Corporation Hungary ZRt (HU) 2014-06-05 US disclosed
US-8664445-B2 Method for providing a secondary or tertiary amine HUNTSMAN INTERNATIONAL LLC (US) 2014-03-04 US disclosed
US-8658831-B2 Method for separating N,N-dialkylbisaminoalkylether from mixtures comprising N,N-dialkylbisaminoalkylbisaminoalkylether and at least one of N,N,N′-trialkylbisaminoalkylether and N,N,N′,N′-tetraalkylbisaminoalkylether HUNTSMAN INTERNATIONAL LLC (US) 2014-02-25 US disclosed
EP-2438039-B1 A METHOD FOR SEPARATING N,N-DIALKYLBISAMINOALKYLETHER FROM MIXTURES COMPRISING N,N-DIALKYLBISAMINOALKYLETHER AND AT LEAST ONE OF N,N,N'-TRIALKYLBISAMINOALKYLETHER AND N,N,N',N'-TETRAALKYLBISAMINOALKYLETHER HUNTSMAN CORP HUNGARY ZRT (HU) 2013-07-31 EP disclosed
US-20120130132-A1 METHOD FOR SEPARATING N,N-DIALKYLBISAMINOALKYLETHER FROM MIXTURES COMPRISING N,N-DIALKYLBISAMINOALKYLETHER AND AT LEAST ONE OF N,N,N'-TRIALKYLBISAMINOALKYLETHER AND N,N,N',N'-TETRAALKYLBISAMINOALKYLETHER HUNTSMAN INTERNATIONAL LLC 2012-05-24 US disclosed
EP-2438038-A1 A METHOD FOR PROVIDING A SECONDARY OR TERTIARY AMINE Huntsman Corporation Hungary ZRt. (HU) 2012-04-11 EP disclosed
EP-2438039-A1 A METHOD FOR SEPARATING N,N-DIALKYLBISAMINOALKYLETHER FROM MIXTURES COMPRISING N,N-DIALKYLBISAMINOALKYLETHER AND AT LEAST ONE OF N,N,N'-TRIALKYLBISAMINOALKYLETHER AND N,N,N',N'-TETRAALKYLBISAMINOALKYLETHER Huntsman Corporation Hungary ZRt. (HU) 2012-04-11 EP disclosed
US-20120071622-A1 Method for Providing a Secondary or Tertiary Amine Huntsman Corporation Hungary ZRt (HU) 2012-03-22 US disclosed
WO-2010139520-A1 A Method for Separating N,N-Dialkylbisaminoalkylether from Mixtures Comprising N,N-Dialkylbisaminoalkylether and at least one of N,N,N'-Trialkylbisaminoalkylether and N,N,N',N'-Tetraalkylbisaminoalkylether HUNTSMAN CORPORATION HUNGARY ZRT. (HU) 2010-12-09 WO disclosed
WO-2010139521-A1 A METHOD FOR PROVIDING A SECONDARY OR TERTIARY AMINE HUNTSMAN CORPORATION HUNGARY ZRT. (HU) 2010-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071622-A1 Method for Providing a Secondary or Tertiary Amine HRH3, HRH4, NPR3 LMNA 2889/4885THRB 129/4885
US-20140155655-A1 Method for providing a secondary or tertiary amine HRH3, HRH4, GLRA3 LMNA 3369/4885THRB 125/4885
US-20120130132-A1 METHOD FOR SEPARATING N,N-DIALKYLBISAMINOALKYLETHER FROM MIXTURES COMPRISING N,N-DIALKYLBISAMINOALKYLETHER AND AT LEAST ONE OF N,N,N'-TRIALKYLBISAMINOALKYLETHER AND N,N,N',N'-TETRAALKYLBISAMINOALKYLETHER NCLN, NCL, DNPH1 LMNA 84/4885THRB 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.