Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 8/20 | 0.40 |
| ▸ | MMP1 | P03956 | 6/20 | 0.40 |
| ▸ | MMP9 | P14780 | 6/20 | 0.40 |
| ▸ | MMP12 | P39900 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7951874 | 0.84 | PLCG1 (0.40) | MMP13MMP1MMP9MMP12MMP2 | |
| SCHEMBL6929547 | 0.80 | MMP7 (0.52) | BMP1MMP1MMP9MMP2MMP14 | |
| SCHEMBL6934202 | 0.80 | MMP13 (0.53) | BMP1MMP13MMP1MMP9MMP12 | |
| SCHEMBL6932142 | 0.72 | MMP9 (0.51) | MMP13MMP1MMP9MMP2MMP3 | |
| Hydroxyamine SCHEMBL7553524 | 0.69 | MMP13 (0.51) | MMP13MMP1MMP9MMP12MMP2 | |
| SCHEMBL7324090 | 0.66 | MMP13 (0.71) | MMP13MMP1MMP9MMP12MMP2 | |
| SCHEMBL7553530 | 0.65 | MMP9 (0.52) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL8106699 | 0.65 | LOX (0.47) | — | |
| SCHEMBL7394119 | 0.64 | BMP1 (0.42) | BMP1MMP13MMP1MMP9MMP12 | |
| SCHEMBL14519930 | 0.64 | HSD11B1 (0.39) | MMP13MMP1MMP9MMP12MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342508-B1 | ENZYME INHIBITORS FOR PROTECTION OF CONNECTIVE TISSUES | AMERICAN CYANAMID COMPANY | 2002-01-29 | — | — | US | disclosed |