Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NHERF1 | O14745 | 4/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696259 | 0.88 | NR1H4 (0.56) | MEN1KMT2AALDH1A1PPARGNR1H4 | |
| SCHEMBL7696457 | 0.80 | AKR1C3 (0.51) | PKMMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7695539 | 0.79 | PPARG (0.54) | L3MBTL1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7690950 | 0.76 | PPARG (0.56) | PKMMEN1KMT2AALDH1A1POLB | |
| SCHEMBL7689583 | 0.75 | KMT2A (0.54) | L3MBTL1PKMMEN1KMT2AKDM4E | |
| SCHEMBL11887786 | 0.75 | PYGL (0.62) | L3MBTL1PKMMEN1KMT2AKDM4E | |
| SCHEMBL11596892 | 0.74 | L3MBTL1 (0.66) | L3MBTL1PKMMEN1KMT2AKDM4E | |
| SCHEMBL17503590 | 0.74 | KDM4E (0.53) | PKMKDM4EALDH1A1GAA | |
| SCHEMBL7697855 | 0.71 | LMNA (0.38) | L3MBTL1PPARGNR1H4HSD17B1LMNA | |
| SCHEMBL6265712 | 0.70 | L3MBTL1 (0.78) | L3MBTL1PKMMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053544-A1 | PHARMACEUTICAL USES AND SYNTHESIS OF NICOTINANILIDE-N-OXIDES | DARWIN DISCOVERY LTD. (GB) | 2002-07-11 | — | — | WO | disclosed |