Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695539 | 0.84 | PPARG (0.54) | PPARGNR1H4RAB9ALMNAHDAC8 | |
| SCHEMBL7697263 | 0.76 | L3MBTL1 (0.50) | PPARGPPARANR1H4LMNAALDH1A1 | |
| SCHEMBL13561126 | 0.75 | HDAC1 (0.79) | PPARGPPARANR1H4RAB9ALMNA | |
| SCHEMBL7696259 | 0.75 | NR1H4 (0.56) | PPARGPPARANR1H4RAB9AALDH1A1 | |
| SCHEMBL7689583 | 0.74 | KMT2A (0.54) | RAB9ALMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1277038 | 0.73 | CA12 (0.61) | PPARGPPARANR1H4RAB9ALMNA | |
| SCHEMBL2900306 | 0.72 | PYGL (0.83) | HDAC8HDAC1HDAC6 | |
| SCHEMBL10742633 | 0.72 | CA12 (0.64) | PPARGPPARANR1H4RAB9ALMNA | |
| SCHEMBL10319139 | 0.72 | DYRK1A (0.84) | PPARGPPARANR1H4RAB9ALMNA | |
| SCHEMBL20053685 | 0.71 | LTB4R (0.64) | RAB9ALMNAHDAC8HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053544-A1 | PHARMACEUTICAL USES AND SYNTHESIS OF NICOTINANILIDE-N-OXIDES | DARWIN DISCOVERY LTD. (GB) | 2002-07-11 | — | — | WO | disclosed |