Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31032981 | 0.76 | KDM4E (0.66) | KDM4EALDH1A1GAASMN1; SMN2HPGD | |
| SCHEMBL17770626 | 0.76 | KDM4E (0.55) | KDM4ENAPRTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7696457 | 0.74 | AKR1C3 (0.51) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7697263 | 0.74 | L3MBTL1 (0.50) | KDM4EALDH1A1GAAPKM | |
| SCHEMBL4230546 | 0.74 | KDM4E (0.53) | KDM4ENAPRTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL2594966 | 0.74 | SPR (0.56) | KDM4ENAPRTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL31547664 | 0.74 | KDM4E (0.53) | KDM4ENAPRTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL17844580 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL25149305 | 0.72 | KDM4E (0.65) | KDM4EALDH1A1GAASMN1; SMN2RXFP1 | |
| SCHEMBL25075360 | 0.72 | ALDH1A1 (0.57) | KDM4EALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10234764-B2 | Electron beam resist composition | THE UNIVERSITY OF MANCHESTER (GB) | 2019-03-19 | — | — | US | claimed |
| EP-3177966-B1 | ELECTRON BEAM RESIST COMPOSITION | UNIV MANCHESTER (GB) | 2019-03-13 | — | — | EP | claimed |
| US-20170235227-A1 | ELECTRON BEAM RESIST COMPOSITION | THE UNIVERSITY OF MANCHESTER (GB) | 2017-08-17 | — | — | US | claimed |
| EP-3177966-A1 | ELECTRON BEAM RESIST COMPOSITION | The University of Manchester (GB) | 2017-06-14 | — | — | EP | claimed |
| WO-2016020650-A1 | ELECTRON BEAM RESIST COMPOSITION | THE UNIVERSITY OF MANCHESTER (GB) | 2016-02-11 | — | — | WO | claimed |
| US-20250361223-A1 | AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LTD (CN) | 2025-11-27 | — | — | US | disclosed |
| US-12435062-B2 | Amide compounds and uses thereof | HUTCHISON MEDIPHARMA LIMITED (CN) | 2025-10-07 | — | — | US | disclosed |
| CN-117777103-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117720520-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117720519-A | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117377665-A | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115315422-B | Amide compound and application thereof | 和记黄埔医药（上海）有限公司 | 2023-11-07 | — | — | CN | disclosed |
| EP-3561596-A1 | ANTISCATTERING RESIST COMPOSITION AND METHOD FOR PERFORMING LITHOGRAPHY | The University Of Manchester (GB) | 2019-10-30 | — | — | EP | disclosed |
| US-20190324370-A1 | ELECTRON BEAM RESIST COMPOSITION | THE UNIVERSITY OF MANCHESTER (GB) | 2019-10-24 | — | — | US | disclosed |
| US-10234764-B2 | Electron beam resist composition | THE UNIVERSITY OF MANCHESTER (GB) | 2019-03-19 | — | — | US | disclosed |
| EP-3177966-B1 | ELECTRON BEAM RESIST COMPOSITION | UNIV MANCHESTER (GB) | 2019-03-13 | — | — | EP | disclosed |
| EP-3356889-A1 | RESIST COMPOSITION | The University Of Manchester (GB) | 2018-08-08 | — | — | EP | disclosed |
| US-20170235227-A1 | ELECTRON BEAM RESIST COMPOSITION | THE UNIVERSITY OF MANCHESTER (GB) | 2017-08-17 | — | — | US | disclosed |
| EP-3177966-A1 | ELECTRON BEAM RESIST COMPOSITION | The University of Manchester (GB) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016020650-A1 | ELECTRON BEAM RESIST COMPOSITION | THE UNIVERSITY OF MANCHESTER (GB) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435062-B2 | Amide compounds and uses thereof | ASNS, ASS1, NAT1 | KDM4E 1449/4885NAPRT 283/4885ALDH1A1 610/4885 |
| US-20250361223-A1 | AMIDE COMPOUNDS AND USES THEREOF | ASNS, NAT1, AADAC | KDM4E 1690/4885NAPRT 215/4885ALDH1A1 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.