Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 2/20 | 0.47 |
| ▸ | MC3R | P41968 | 2/20 | 0.47 |
| ▸ | MC1R | Q01726 | 2/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5967654 | 0.95 | LTA4H (0.50) | ALDH1A1LMNAMAPTNPSR1TAAR1 | |
| SCHEMBL6192056 | 0.84 | HSD11B1 (0.47) | ALDH1A1LMNAMAPTNPSR1TAAR1 | |
| SCHEMBL2997593 | 0.80 | — | — | |
| SCHEMBL5530480 | 0.80 | — | — | |
| SCHEMBL23802796 | 0.80 | ABCB1 (0.48) | — | |
| Hydrochloric Acid SCHEMBL4766854 | 0.80 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTNPSR1TAAR1 | |
| SCHEMBL6174357 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTNPSR1TAAR1 | |
| SCHEMBL27852994 | 0.79 | OPRD1 (0.51) | ALDH1A1OPRD1LTA4H | |
| SCHEMBL11385902 | 0.79 | RAB9A (0.50) | — | |
| Ammonia Solution, Strong SCHEMBL29243589 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002072582-A1 | METHODS FOR THE SYNTHESIS OF DENSELY FUNCTIONALIZED PYRROLIDINE TEMPLATE LIBRARIES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2002-09-19 | — | — | WO | disclosed |