SCHEMBL7702883

SCHEMBL7702883

Cc1cc(-c2[c]cccc2)cc(C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
ACHE P22303 1/20 0.41
PTGS1 P23219 6/20 0.40
PTGS2 P35354 6/20 0.40
ALOX5 P09917 4/20 0.40
TTR P02766 1/20 0.40
LMNA P02545 1/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 1/20 0.38
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
PKM P14618 1/20 0.36
HSD17B1 P14061 1/20 0.35
HSD17B2 P37059 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
CYTH2 Q99418 1/20 0.34
MEN1 O00255 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9646719 0.81 ACHE (0.32) ACHE
SCHEMBL1141083 0.78 NPC1 (0.39) ACHELMNAHTTALDH1A1MEN1
SCHEMBL6705304 0.78 ACHE (0.35) ACHELMNAALDH1A1ADORA2AADORA1
SCHEMBL5327938 0.74 ACHE (0.39) ACHEPTGS1PTGS2CYP1A2CYP2C9
SCHEMBL27875143 0.73 MEN1 (0.37) ACHELMNAHTTALDH1A1CYTH2
SCHEMBL16432871 0.73 AHR (0.45) CA1CA2PTGS1ALOX5LMNA
SCHEMBL5329094 0.72 KDM4E (0.40) CA1CA2PTGS1PTGS2LMNA
SCHEMBL67548 0.71 ACHE (0.38) ACHELMNAHTTALDH1A1MEN1
SCHEMBL1411316 0.71 MMP3 (0.48) CA1CA2LMNAHTTALDH1A1
SCHEMBL2449602 0.71 ALDH1A1 (0.41) ALOX5HTTALDH1A1CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed