SCHEMBL2449602

SCHEMBL2449602

[c]1ccccc1-c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
SLC22A2 O15244 1/20 0.34
SLC22A1 O15245 1/20 0.34
SLC22A3 O75751 1/20 0.34
SLC6A4 P31645 1/20 0.34
HTT P42858 5/20 0.34
KDM4E B2RXH2 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
RAB9A P51151 3/20 0.34
MAPK1 P28482 2/20 0.34
NPC1 O15118 2/20 0.34
NTSR1 P30989 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
UHRF1 Q96T88 1/20 0.34
EGFR P00533 1/20 0.34
POLB P06746 2/20 0.33
KMO O15229 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26567 0.89 MAOA (0.41) ALDH1A1HTTKMOMAOAMEN1
SCHEMBL589437 0.89 MAOA (0.41) ALDH1A1HTTKMOMAOAMEN1
SCHEMBL769959 0.86 ALDH1A1 (0.45) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL25097 0.86 ALDH1A1 (0.45) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL769634 0.86 ALDH1A1 (0.45) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL2452767 0.86 ESR1 (0.46) ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A
SCHEMBL41140 0.85 ALDH1A1 (0.42) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL38202 0.85 ALDH1A1 (0.42) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL28544762 0.83 ALDH1A1 (0.40) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL28917460 0.82 MKNK1 (0.45) CYP2A6NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989519-A Application of cycloolefin polymer in long afterglow material 重庆理工大学 2022-09-02 CN claimed
EP-1640430-B1 Luminescent material and organic electroluminescent device using the same JNC CORP (JP) 2011-09-21 EP claimed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP claimed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP claimed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US claimed
WO-2024128314-A1 POLYCYCLIC AROMATIC COMPOUND 国立大学法人京都大学 2024-06-20 WO disclosed
US-11800785-B2 Material for organic device and organic electroluminescent device using the same KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-10-24 US disclosed
US-20230276708-A1 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2023-08-31 US disclosed
CN-114989519-B Application of cycloolefin polymer in long afterglow material 重庆理工大学 2023-08-25 CN disclosed
CN-114989519-A Application of cycloolefin polymer in long afterglow material 重庆理工大学 2022-09-02 CN disclosed
CN-114989199-A Polycyclic aromatic compound, and compound, crosslinked product, material, composition and device each containing or using same 学校法人关西学院 2022-09-02 CN disclosed
CN-114989198-A Polycyclic aromatic compound, material for organic device, organic electroluminescent element, display device, and lighting device 学校法人关西学院 2022-09-02 CN disclosed
EP-2177586-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2010-04-21 EP disclosed
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same JNC CORPORATION (JP) 2010-02-04 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed
US-20070212568-A1 Organic Electroluminescent Device CHISSO CORPORATION (JP) 2007-09-13 US disclosed
US-20060110622-A1 Organic electroluminescent device LG ELECTRONICS, INC. (KR) 2006-05-25 US disclosed
EP-1640430-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-03-29 EP disclosed
EP-1624501-A2 Organic electroluminescent device LG Electronics, Inc. (KR) 2006-02-08 EP disclosed
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same CHISSO CORPORATION (JP) 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230276708-A1 Polycyclic aromatic compound ACVR1B, XDH, AHR ALDH1A1 2290/4885CRHBP 2878/4885CRHR2 439/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 ALDH1A1 1152/4885CRHBP 4143/4885CRHR2 4231/4885
US-11800785-B2 Material for organic device and organic electroluminescent device using the same RER1, LEF1, CHRM1 ALDH1A1 913/4885CRHBP 4485/4885CRHR2 2379/4885
US-20060014046-A1 Luminescent material and organic electroluminescent device using the same C1S, EPB41, EPB41L2 ALDH1A1 1227/4885CRHBP 3866/4885CRHR2 2890/4885
US-20100025661-A1 Luminescent material and organic electroluminescent device using the same TRPV3, TRPC3, HVCN1 ALDH1A1 944/4885CRHBP 2248/4885CRHR2 875/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.