SCHEMBL67548

SCHEMBL67548

Cc1ccc(-c2[c]cccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.38
LMNA P02545 2/20 0.38
TSHR P16473 1/20 0.38
ALOX12 P18054 1/20 0.38
RAB9A P51151 6/20 0.36
NPC1 O15118 5/20 0.36
HPGD P15428 4/20 0.36
TDP1 Q9NUW8 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NFKB1 P19838 2/20 0.36
NFKB2 Q00653 2/20 0.36
RELA Q04206 2/20 0.36
POLB P06746 1/20 0.36
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
MITF O75030 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7819321 0.92 LMNA (0.37) ACHELMNATSHRALOX12RAB9A
SCHEMBL3319820 0.89 MAPT (0.43) LMNARAB9ANPC1TDP1SMN1; SMN2
SCHEMBL25097 0.81 ALDH1A1 (0.45) TDP1SMN1; SMN2ALDH1A1MAPT
SCHEMBL769959 0.81 ALDH1A1 (0.45) TDP1SMN1; SMN2ALDH1A1MAPT
SCHEMBL769634 0.81 ALDH1A1 (0.45) TDP1SMN1; SMN2ALDH1A1MAPT
SCHEMBL38202 0.80 ALDH1A1 (0.42) LMNARAB9ANPC1TDP1ALDH1A1
SCHEMBL183516 0.80 ALDH1A1 (0.35) RAB9AALDH1A1MEN1KMT2A
SCHEMBL41140 0.80 ALDH1A1 (0.42) LMNARAB9ANPC1TDP1ALDH1A1
SCHEMBL6705304 0.80 ACHE (0.35) ACHELMNATSHRALOX12ALDH1A1
SCHEMBL28544762 0.78 ALDH1A1 (0.40) LMNARAB9ANPC1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3378853-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2024-04-17 EP claimed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US claimed
CN-113583042-B Preparation method of phosphoryl fluoride compound 烟台大学 2023-08-29 CN claimed
CN-110540526-B Carane acidyl 1,2, 3-triazole compound and preparation method and application thereof 广西大学 2022-08-30 CN claimed
US-RE49118-E1 Material for organic electroluminescence device and electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2022-06-28 US claimed
CN-114502543-A Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof 拜欧斯瑞克斯公司 2022-05-13 CN claimed
CN-114206886-A Luminescent gold (III) compound, method for preparing same, and organic light emitting device using same 广东聚华印刷显示技术有限公司 2022-03-18 CN claimed
EP-3339293-B1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-08-11 EP claimed
EP-3388438-B1 SPIRO-STRUCTURED COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-08-11 EP claimed
EP-3305765-B1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-08-04 EP claimed
EP-1696015-A1 LIGHT-EMITTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DEVICE USING SAME, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2006-08-30 EP claimed
US-7053056-B2 C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases IDUN PHARMACEUTICALS, INC. (US) 2006-05-30 US claimed
US-6544951-B2 Antiinflammatory agents; autoimmune diseases, nervous system degradation IDUN PHARMACEUTICALS, INC. 2003-04-08 US claimed
EP-0838458-A1 NOVEL REAGENT FOR TETRAZOLE SYNTHESIS AND PROCESS FOR PRODUCING TETRAZOLES THEREWITH CHUGOKU KAYAKU KABUSHIKI KAISHA (JP) 1998-04-29 EP claimed
EP-0414299-B1 Biocidal azoxime compounds SHELL INT RESEARCH (NL) 1994-06-15 EP claimed
EP-0294220-B1 Photopolymerizable composition HITACHI CHEMICAL CO LTD (JP) 1994-05-25 EP claimed
US-5169856-A Cholinesterase antagonists TAKEDA CHEMICAL INDUSTRIES, INC. (JP) 1992-12-08 US claimed
EP-0295044-B1 PHOTOINITIATOR AND PHOTOPOLYMERIZABLE COMPOSITION USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1992-04-22 EP claimed
EP-0295044-A2 Photoinitiator and photopolymerizable composition using the same Hitachi Chemical Co., Ltd. (JP) 1988-12-14 EP claimed
EP-0294220-A2 Photopolymerizable composition Hitachi Chemical Co., Ltd. (JP) 1988-12-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 ACHE 2339/4885LMNA 3261/4885TSHR 2662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.