SCHEMBL6705304

SCHEMBL6705304

Cc1cc(C)cc(-c2[c]cccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.35
BRD9 Q9H8M2 1/20 0.33
BRD7 Q9NPI1 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31
ALOX12 P18054 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2115058 0.83 ACHE (0.42) ACHEALDH1A1MAPTTSHR
SCHEMBL67548 0.80 ACHE (0.38) ACHEALDH1A1MAPTLMNATSHR
SCHEMBL21295672 0.79 CYP2A6 (0.46) CYP2A6
SCHEMBL28000910 0.79 RAB9A (0.39) ACHEALDH1A1MAPTTSHR
SCHEMBL7702883 0.78 CA1 (0.48) ACHEADORA2AADORA1ALDH1A1LMNA
SCHEMBL9646719 0.78 ACHE (0.32) ACHE
SCHEMBL1070016 0.77 CYP1A2 (0.38) ACHETSHRCYP1A2CYP2A6PSMB5
SCHEMBL7138582 0.76 ACHE (0.36) ACHEALDH1A1RXRARXRBTSHR
SCHEMBL2449602 0.76 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP2A6
SCHEMBL1141083 0.75 NPC1 (0.39) ACHEALDH1A1MAPTLMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
CN-114989519-A Application of cycloolefin polymer in long afterglow material 重庆理工大学 2022-09-02 CN claimed
CN-104710381-A Novel 3-hydroxy-5-arylisothiazole derivative MOCHIDA PHARM CO LTD 2015-06-17 CN claimed
US-6288091-B1 COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX BOEHRINGER INGELHEIM LTD. (CA) 2001-09-11 US claimed
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN disclosed
CN-117044428-A Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element 东曹株式会社 2023-11-10 CN disclosed
CN-114989519-B Application of cycloolefin polymer in long afterglow material 重庆理工大学 2023-08-25 CN disclosed
CN-114989519-A Application of cycloolefin polymer in long afterglow material 重庆理工大学 2022-09-02 CN disclosed
CN-110099878-A Compound glass sealing material and compound glass DIC株式会社 2019-08-06 CN disclosed
CN-106795092-B Epoxy ester compound, cellulose ester resin composition, optical film and liquid crystal display device DIC株式会社 2019-05-17 CN disclosed
CN-106795092-A Epoxy ester compound, cellulose ester resin composition, optical film and liquid crystal display device DIC株式会社 2017-05-31 CN disclosed
CN-104710381-A Novel 3-hydroxy-5-arylisothiazole derivative MOCHIDA PHARM CO LTD 2015-06-17 CN disclosed
CN-104140445-A Red organic electrophosphorescent material iridium metal complex, preparation method thereof, and organic electroluminescent device OCEANS KING LIGHTING SCIENCE 2014-11-12 CN disclosed
CN-102712610-A Novel 3-hydroxy-5-arylisothiazole derivatives MOCHIDA PHARM CO LTD 2012-10-03 CN disclosed
CN-101955690-A The manufacture method of dispersible pigment dispersion SUMITOMO CHEMICAL CO 2011-01-26 CN disclosed
EP-1425283-A1 NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF Bayer HealthCare AG (DE) 2004-06-09 EP disclosed
WO-2003018589-A1 NOVEL 4-AMINOFUROPYRIMIDINES AND THE USE THEREOF BAYER HEALTHCARE AG (DE) 2003-03-06 WO disclosed
US-6288091-B1 COMPOUNDS SUCH AS 2,2,2-TRICHLOROETHYL N-(4-(2-AMINO-4-THIAZOLYL)-PHENYL)CARBAMATE THAT INHIBIT THE HERPES HELCASE-PRIMASE ENZYME COMPLEX BOEHRINGER INGELHEIM LTD. (CA) 2001-09-11 US disclosed
US-4808607-A ATHEROSCLEROSIS, HYPERLIPOPROTEINEMIA SANDOZ PHARM. CORP. (US) 1989-02-28 US disclosed
US-4755606-A Imidazolyl-3,5-di-(diphenyl-butylsilyloxy) carboxylic acid ester intermediates SANDOZ PHARM. CORP. (US) 1988-07-05 US disclosed