Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770088 | 0.86 | LMNA (0.36) | ALDH1A1HPGDALOX5 | |
| SCHEMBL11763851 | 0.72 | MAOA (0.46) | MAOAMAOBALDH1A1HPGDPTGS2 | |
| Hydrogen Sulfide SCHEMBL27721391 | 0.70 | MAOA (0.45) | MAOAMAOBALDH1A1HPGDPTGS2 | |
| SCHEMBL11767098 | 0.70 | PTGS2 (0.45) | MAOAMAOBALDH1A1HPGDPTGS2 | |
| SCHEMBL2414534 | 0.70 | ALDH1A1 (0.53) | MAOAMAOBALDH1A1HPGD | |
| SCHEMBL5713298 | 0.70 | ALDH1A1 (0.53) | MAOAMAOBALDH1A1HPGD | |
| SCHEMBL29546908 | 0.68 | ALDH1A1 (0.45) | MAOAMAOBALDH1A1HPGDPTGS2 | |
| SCHEMBL15418803 | 0.68 | ALDH1A1 (0.45) | MAOAMAOBALDH1A1HPGDPTGS2 | |
| Hydrogen Sulfide SCHEMBL16176783 | 0.68 | MAPK1 (0.38) | MAOAMAOBALDH1A1HPGDPTGS1 | |
| SCHEMBL8749824 | 0.68 | MAPT (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |