Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703318 | 0.88 | RET (0.39) | RET | |
| SCHEMBL8991124 | 0.86 | PI4KB (0.35) | RET | |
| SCHEMBL8990961 | 0.79 | KDM4E (0.44) | RET | |
| SCHEMBL8991126 | 0.78 | RET (0.36) | RETENPP1 | |
| SCHEMBL7703321 | 0.78 | RET (0.38) | RETENPP1 | |
| SCHEMBL7701687 | 0.77 | LRRK2 (0.54) | RET | |
| SCHEMBL8991281 | 0.76 | ENPP1 (0.39) | RETENPP1 | |
| SCHEMBL8991290 | 0.76 | RET (0.33) | RET | |
| SCHEMBL8991267 | 0.74 | KDM4E (0.48) | RET | |
| SCHEMBL7701707 | 0.74 | SRC (0.36) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |