Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991298 | 0.88 | RET (0.33) | P2RY1RET | |
| SCHEMBL7701709 | 0.87 | RET (0.36) | RET | |
| SCHEMBL8991228 | 0.86 | PDE4A (0.37) | RET | |
| SCHEMBL8991176 | 0.80 | XDH (0.31) | XDH | |
| SCHEMBL8990972 | 0.79 | MEN1 (0.46) | — | |
| SCHEMBL8991147 | 0.78 | GAA (0.39) | — | |
| SCHEMBL8991163 | 0.78 | YTHDC1 (0.31) | — | |
| SCHEMBL8991004 | 0.78 | YTHDC1 (0.31) | — | |
| SCHEMBL8991328 | 0.78 | ALDH1A1 (0.44) | — | |
| SCHEMBL7700322 | 0.78 | ADK (0.33) | XDHP2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |