Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | GLI1 | P08151 | 1/20 | 0.43 |
| ▸ | GLI2 | P10070 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511395 | 0.89 | CA1 (0.53) | CA2CTSSCTSKCTSLCTSB | |
| SCHEMBL7513132 | 0.83 | CA2 (0.52) | CA2CTSSCTSKCTSLCTSB | |
| SCHEMBL9214875 | 0.83 | CTSS (0.51) | CA2KLK7KLK5CTSSCTSK | |
| SCHEMBL7693003 | 0.83 | KLK7 (0.56) | CA2KLK7KLK5CTSKCA1 | |
| SCHEMBL7404441 | 0.81 | KLK7 (0.51) | CA2KLK7KLK5CTSSCTSK | |
| SCHEMBL7689080 | 0.80 | CTSS (0.65) | CA2CTSSCTSKCTSLCTSB | |
| SCHEMBL26294280 | 0.80 | CA5A (0.55) | CA2CTSSCTSKCTSLCTSB | |
| SCHEMBL15259723 | 0.80 | MEN1 (0.56) | KLK7KLK5CTSSCTSKCTSL | |
| SCHEMBL13108630 | 0.79 | CTSS (0.57) | KLK7KLK5CTSSCTSKCTSL | |
| SCHEMBL7518690 | 0.79 | CA2 (0.53) | CA2CTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |