Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.51 |
| ▸ | CTSK | P43235 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224778 | 0.87 | PSMB5 (0.51) | CTSSCTSKCA2KLK7KLK5 | |
| SCHEMBL7404441 | 0.87 | KLK7 (0.51) | CTSSCTSKCA2KLK7KLK5 | |
| SCHEMBL15259723 | 0.85 | MEN1 (0.56) | CTSSCTSKKLK7KLK5CTSL | |
| SCHEMBL9224769 | 0.85 | KLK7 (0.45) | CTSSCTSKCA2KLK7KLK5 | |
| SCHEMBL5656256 | 0.84 | CTSK (0.54) | CTSSCTSKCA2KLK7KLK5 | |
| SCHEMBL26294280 | 0.83 | CA5A (0.55) | CTSSCTSKCA2CA5ACTSL | |
| SCHEMBL10825282 | 0.83 | MEN1 (0.62) | CTSSCTSKKLK7KLK5 | |
| Trifluoroacetic Acid SCHEMBL7703706 | 0.83 | CA2 (0.49) | CTSSCTSKCA2KLK7KLK5 | |
| SCHEMBL13108630 | 0.83 | CTSS (0.57) | CTSSCTSKKLK7KLK5PPARA | |
| SCHEMBL9220637 | 0.83 | CASP1 (0.55) | CTSSCTSKCA2KLK7KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |