Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 7/20 | 0.35 |
| ▸ | CA2 | P00918 | 7/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP13 | P45452 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5372804 | 0.99 | HSD11B1 (0.37) | HSD11B1ALDH1A1CA1CA2RORA | |
| SCHEMBL114859 | 0.94 | ALDH1A1 (0.39) | HSD11B1ALDH1A1CA1CA2RORA | |
| SCHEMBL448974 | 0.93 | ALDH1A1 (0.38) | HSD11B1ALDH1A1CA1CA2RORA | |
| SCHEMBL8038207 | 0.93 | ALDH1A1 (0.38) | HSD11B1ALDH1A1CA1CA2RORA | |
| SCHEMBL7570325 | 0.90 | ALDH1A1 (0.36) | HSD11B1ALDH1A1CA1CA2RORA | |
| SCHEMBL2438900 | 0.90 | ALDH1A1 (0.42) | HSD11B1ALDH1A1CA1CA2RORA | |
| SCHEMBL51422 | 0.89 | CA2 (0.38) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL213386 | 0.87 | CA2 (0.40) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL59303 | 0.87 | CA2 (0.40) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2437858 | 0.87 | HSD11B1 (0.34) | HSD11B1ALDH1A1CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358665-B1 | ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE | CLARIANT INTERNATIONAL LTD. (CH) | 2002-03-19 | — | — | US | disclosed |
| EP-1033624-A1 | RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE | Clariant International Ltd. (CH) | 2000-09-06 | — | — | EP | disclosed |