SCHEMBL448974

SCHEMBL448974

CC(C)(C)c1ccc([I+]c2ccc(C(C)(C)C)cc2)cc1.O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
RORA P35398 1/20 0.36
CA2 P00918 9/20 0.36
ACHE P22303 1/20 0.35
CA1 P00915 8/20 0.35
LMNA P02545 2/20 0.35
GAA P10253 1/20 0.35
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
MMP13 P45452 1/20 0.34
HSD11B1 P28845 3/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
NPC1 O15118 1/20 0.34
GMNN O75496 1/20 0.34
DRD1 P21728 1/20 0.34
DRD3 P35462 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038207 1.00 ALDH1A1 (0.38) ALDH1A1RORACA2ACHECA1
SCHEMBL114859 0.98 ALDH1A1 (0.39) ALDH1A1RORACA2ACHECA1
SCHEMBL5372804 0.95 HSD11B1 (0.37) ALDH1A1RORACA2ACHECA1
SCHEMBL7570325 0.94 ALDH1A1 (0.36) ALDH1A1RORACA2ACHECA1
SCHEMBL2438900 0.94 ALDH1A1 (0.42) ALDH1A1RORACA2ACHECA1
SCHEMBL7708260 0.93 HSD11B1 (0.38) ALDH1A1RORACA2ACHECA1
SCHEMBL548235 0.88 CA2 (0.38) ALDH1A1CA2CA1MMP1MMP2
SCHEMBL2438901 0.87 RORA (0.38) ALDH1A1RORAACHELMNAGAA
SCHEMBL29625803 0.86 ALDH1A1 (0.31) ALDH1A1RORACA2CA1
SCHEMBL548591 0.86 KIF11 (0.38) ALDH1A1CA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 711 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662274-B2 Self-immolative polymers, articles thereof, and methods of making and using same GEORGIA TECH RESEARCH CORPORATION (US) 2020-05-26 US claimed
US-20180155483-A1 SELF-IMMOLATIVE POLYMERS, ARTICLES THEREOF, AND METHODS OF MAKING AND USING SAME GEORGIA TECH RESEARCH CORPORATION 2018-06-07 US claimed
US-9740096-B2 Positive-tone, chemically amplified, aqueous-developable, permanent dielectric GEORGIA TECH RESEARCH CORPORATION (US) 2017-08-22 US claimed
US-20150160551-A1 POSITIVE-TONE, CHEMICALLY AMPLIFIED, AQUEOUS-DEVELOPABLE, PERMANENT DIELECTRIC GEORGIA TECH RESEARCH CORPORATION (US) 2015-06-11 US claimed
EP-4747233-A2 COMPOUNDS, COMPOSITIONS CONTAINING COMPOUNDS, AND METHODS OF MANUFACTURING RESIST MEMBRANES Merck Patent GmbH (DE) 2026-05-27 EP disclosed
US-12631962-B2 Resist composition and method for forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2026-05-19 US disclosed
US-12624392-B2 Molecular array generation using photoresist 10X GENOMICS, INC. (US) 2026-05-12 US disclosed
US-20250362597-A1 RESIST COMPOSITION AND RESIST FILM FORMING METHOD USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-11-27 US disclosed
US-20250321485-A1 RESIST AUXILIARY FILM COMPOSITION, AND PATTERN FORMING METHOD USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-10-16 US disclosed
US-12393115-B2 Positive working photosensitive material MERCK PATENT GMBH (DE) 2025-08-19 US disclosed
EP-4516394-A2 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2025-03-05 EP disclosed
WO-2025017121-A2 COMPOUNDS, COMPOSITIONS CONTAINING COMPOUNDS, AND METHODS OF MANUFACTURING RESIST MEMBRANES MERCK PATENT GMBH (DE) 2025-01-23 WO disclosed
US-6203965-B1 USEFUL AS DEEP ULTRAVIOLET RADIATION PHOTORESISTS SHIPLEY COMPANY, L.L.C. 2001-03-20 US disclosed
US-6200728-B1 Photoresist compositions comprising blends of photoacid generators SHIPLEY COMPANY, L.L.C. 2001-03-13 US disclosed
EP-1041442-A1 Chemical amplification type positive resist SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-04 EP disclosed
EP-1030221-A1 Photoresist compositions comprising blends of photoacid generators Shipley Company LLC (US) 2000-08-23 EP disclosed
US-6048672-A RELIEF IMAGES ON SUBSTRATES WITH TITANIUM NITRIDE SURFACES, HEATING, COATING, EXPOSURE AND DEVELOPMENT SHIPLEY COMPANY, L.L.C. (US) 2000-04-11 US disclosed
EP-0987600-A1 Antireflective coating compositions Shipley Company LLC (US) 2000-03-22 EP disclosed
US-6037107-A EXPOSING TO ACTIVATION RADIATION A POSITIVE WORKING PHOTORESIST COMPRISING AN ALKALI SOLUBLE RESIN SUBSTITUTED WITH AN ACID LABILE BLOCKING GROUP TO GENERATE HALOGENATED SULFONIC ACID BY PHOTOLYSIS SHIPLEY COMPANY, L.L.C. (US) 2000-03-14 US disclosed
EP-0938029-A2 Methods using photoresist compositions and articles produced therewith Shipley Company LLC (US) 1999-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12631962-B2 Resist composition and method for forming resist pattern TERB1, TERF2, LSM8 ALDH1A1 1639/4885RORA 1130/4885CA2 677/4885
US-12624392-B2 Molecular array generation using photoresist POLL, LIG4, LIG3 ALDH1A1 189/4885RORA 2222/4885CA2 2965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.