SCHEMBL7708628

SCHEMBL7708628

CC(C)(C)c1ccc([I+]c2ccccc2)cc1.O=S(=O)([O-])C(F)(F)C(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 7/20 0.38
ALDH1A1 P00352 7/20 0.36
MAPT P10636 1/20 0.36
MAOA P21397 1/20 0.34
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
SPPL2A Q8TCT8 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
ACHE P22303 1/20 0.33
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
HSD17B3 P37058 1/20 0.32
UQCRB P14927 1/20 0.32
HSD17B2 P37059 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7705618 0.95 ALDH1A1 (0.38) HSD11B1ALDH1A1MAPTACHETP53
SCHEMBL7708128 0.89 GPR3 (0.34)
SCHEMBL7708455 0.86 GPR3 (0.35) ALDH1A1MAPTSMN1; SMN2L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL1002309 0.84 HSD11B1 (0.41) HSD11B1ALDH1A1MAPTMAOAACHE
Trifluoromethanesulfonic Acid SCHEMBL1270048 0.84 HSD11B1 (0.41) HSD11B1ALDH1A1MAPTMAOAACHE
SCHEMBL7702806 0.82 HSD11B1 (0.38) HSD11B1ALDH1A1MAPTMAOATP53
Toliodium SCHEMBL7708774 0.80 AGER (0.36) ALDH1A1ACHESMN1; SMN2
Tert-Butylbenzene SCHEMBL2964334 0.80 GPR3 (0.41) HSD11B1ALDH1A1MAPTACHENPC1
SCHEMBL503160 0.78 ALDH1A1 (0.36) HSD11B1ALDH1A1MAPTACHETP53
Trifluoromethanesulfonic Acid SCHEMBL36627 0.78 ALDH1A1 (0.46) HSD11B1ALDH1A1MAPTACHETP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed