SCHEMBL7708747

SCHEMBL7708747

Cc1cc(-c2[c]ccc(C(C)(C)C)c2-c2cc(C)c(O)c(C)c2)cc(C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 1/20 0.47
CA2 P00918 4/20 0.39
CA1 P00915 2/20 0.39
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
ALDH1A1 P00352 4/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TYR P14679 2/20 0.35
POLB P06746 1/20 0.35
PTGS1 P23219 3/20 0.34
PTGS2 P35354 2/20 0.34
ACHE P22303 1/20 0.33
ALOX5 P09917 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
G6PD P11413 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7702892 0.77 TSHR (0.34) PTGS1PTGS2TSHR
SCHEMBL7708522 0.76 SENP1 (0.37) CYP2C9CA2CA1ALDH1A1TYR
SCHEMBL7702879 0.75 CA1 (0.39) CA2CA1PTGS1PTGS2ACHE
SCHEMBL5891289 0.71 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2MAPTTSHRTDP1
SCHEMBL7708203 0.69 MEN1 (0.31) MEN1KMT2A
SCHEMBL13779468 0.68 CYP1A2 (0.87) CYP1A2CYP2C9CYP2C19CA2CA1
SCHEMBL7702914 0.67 CA1 (0.45) CYP1A2CYP2C9CYP2C19CA2CA1
SCHEMBL8204676 0.67 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2MEN1KMT2AALOX15
SCHEMBL7711403 0.67 PTGS2 (0.36) CA2CA1ALDH1A1SMN1; SMN2PTGS2
SCHEMBL3236808 0.66 CA2 (0.48) CYP1A2CYP2C9CYP2C19CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed