Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7705992 | 0.99 | HPGD (0.45) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7436334 | 0.88 | HTT (0.50) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7711835 | 0.81 | ADORA2A (0.64) | RAB9AADORA2AKDM4EKMT2AMAPT | |
| SCHEMBL7480538 | 0.80 | ADORA2A (0.65) | ALDH1A1ADORA2A | |
| SCHEMBL7430368 | 0.79 | ADORA2A (0.66) | ALDH1A1ADORA2AADORA3 | |
| SCHEMBL7423524 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL6868104 | 0.77 | ADORA2A (0.72) | HPGDALDH1A1ADORA2AMEN1KMT2A | |
| SCHEMBL6867145 | 0.76 | ADORA2A (0.71) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7434291 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7705975 | 0.75 | GBA1 (0.48) | KDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |