Iopamidol

Iopamidol

SCHEMBL9490264

C[C@H](O)C(=O)Nc1c(I)c(C(=O)NC(CO)CO)c(I)c(C(=O)NC(CO)CO)c1I.NC(=O)c1cccc(C(N)=O)c1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.72
F3 P13726 3/20 0.40
PARP1 P09874 5/20 0.34
PARP10 Q53GL7 2/20 0.34
MAPK14 Q16539 2/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAP3K5 Q99683 1/20 0.32
MAP3K7 O43318 1/20 0.32
POLB P06746 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
F10 P00742 1/20 0.32
PRSS1 P07477 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7709204 0.88 LMNA (0.90) LMNA
Iopamidol SCHEMBL27781 0.85 LMNA (1.00) LMNA
Iopamidol SCHEMBL471484 0.85 LMNA (1.00) LMNA
Iopamidol SCHEMBL7101453 0.85 LMNA (1.00) LMNA
Iopamidol SCHEMBL2140144 0.81 LMNA (0.92) LMNA
Iopamidol SCHEMBL3424448 0.81 LMNA (0.92) LMNA
SCHEMBL22006124 0.81 LMNA (0.92) LMNA
SCHEMBL13283626 0.81 LMNA (0.90) LMNA
SCHEMBL31409203 0.81 LMNA (0.90) LMNA
SCHEMBL22661225 0.78 LMNA (0.85) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524265-A1 CONTRAST MEDIUM, PROCESS FOR ITS PREPARATION AND APPLICATION TO IMAGERY GUERBET S.A. (FR) 1993-01-27 EP disclosed
WO-1991016080-A1 CONTRAST MEDIUM, PROCESS FOR ITS PREPARATION AND APPLICATION TO IMAGERY GUERBET S.A. (FR) 1991-10-31 WO disclosed