Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.48 |
| ▸ | HPGDS | O60760 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046023 | 0.87 | ACE (0.60) | ACECA2CA1MMEECE1 | |
| SCHEMBL7709762 | 0.86 | ACE (0.47) | ACELNPEPHPGDSCA2CA1 | |
| SCHEMBL7511099 | 0.85 | ACE (0.64) | ACELNPEPHPGDS | |
| SCHEMBL5652507 | 0.84 | ACE (0.52) | ACELNPEPHPGDSCA2CA1 | |
| SCHEMBL4621148 | 0.84 | MAPT (0.55) | ACELNPEPHPGDSCA2CA1 | |
| SCHEMBL7523142 | 0.83 | ACE (0.50) | ACELNPEPHPGDSERAP2ERAP1 | |
| SCHEMBL4623715 | 0.83 | GPR132 (0.53) | ACEHPGDSMRGPRX4SMN1; SMN2 | |
| SCHEMBL2246648 | 0.80 | ACE (0.47) | ACELNPEPHPGDSCA2CA1 | |
| SCHEMBL2246727 | 0.80 | HPGDS (0.51) | ACELNPEPHPGDSCA2CA1 | |
| SCHEMBL4919347 | 0.80 | MME (0.56) | MMEECE1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |